Rate of force production and relaxation is impaired in patients with focal hand dystonia
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چکیده
منابع مشابه
Homeostatic-like plasticity of the primary motor hand area is impaired in focal hand dystonia.
The excitability of inhibitory circuits in patients with writer's cramp is reduced at multiple levels within the sensorimotor system, including the primary motor hand area (M1). Although this may play a major role in the pathophysiology of writer's cramp, it is still unclear what factors may cause the imbalance between inhibition and excitation to arise. One possibility is that homeostatic mech...
متن کاملImpaired modulation of intracortical inhibition in focal hand dystonia.
Previous studies have shown that intracortical inhibition (ICI) plays an important role in shaping the output from primary motor cortex, and that ICI may be impaired in people with Focal Hand Dystonia (FHD). This study explored the muscle-specificity and temporal modulation of ICI during the performance of a phasic index finger flexion task. Eight control subjects and seven with FHD were asked ...
متن کاملKinesthesia is impaired in focal dystonia.
Parkinson's disease (PD) and focal dystonia (FD) are both predominantly characterized by motor symptoms. Also, recent research has shown that sensory processing is impaired in both movement disorders. FD is characterized by involuntary movements and abnormal limb postures; thus, abnormal kinesthesia could be involved in the pathogenesis. We examined passive index finger movements in patients wi...
متن کاملSurround inhibition depends on the force exerted and is abnormal in focal hand dystonia.
There is evidence that surround inhibition (SI), a neural mechanism to enhance contrast between signals, may play a role in primary motor cortex during movement initiation, while it is deficient in patients with focal hand dystonia (FHD). To further characterize SI with respect to different force levels, single- and paired-pulse transcranial magnetic stimulation was applied at rest and during i...
متن کاملQuantitative Assessment of Hand Dysfunction in Patients with Early Parkinson’s Disease and Focal Hand Dystonia
OBJECTIVE Motor impairments related to hand function are common symptoms in patients with movement disorders, such as Parkinson's disease (PD) and focal hand dystonia (FHD). However, hand dysfunction has not been quantitatively assessed as a clinical tool for screening patient groups from healthy controls (HCs). The aim of our study was 1) to quantitatively assess hand dysfunction in patients w...
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ژورنال
عنوان ژورنال: Parkinsonism & Related Disorders
سال: 2006
ISSN: 1353-8020
DOI: 10.1016/j.parkreldis.2006.01.008